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Scientific
Advisory Board
Timothy M. Block,
Ph.D.
Dr.
Block is the volunteer President and Director for the Institute
for Hepatitis and Virus Research, and the Hepatitis B
Foundation; Director, Drexel Institute for Biotechnology and
Virology Research; and Professor, Microbiology and Immunology,
Drexel University College of Medicine.
After learning of a moving
personal story, Dr.
Timothy Block
shifted his professional scientific direction and dedicated
himself to the pursuit of finding a cure for disease caused by
the hepatitis B virus. With his wife Joan, and Jan and Paul
Witte of
New Hope
PA, he helped establish the Hepatitis B Foundation in 1991, the only nonprofit organization solely dedicated to the cause
of hepatitis B. Their public advocacy initiative has resulted in
raising awareness of the worldwide problem of hepatitis B around
the globe, and is highlighted in the introduction of laws in the
United States
requiring hepatitis B vaccination of school children, most
notably Act 15 in
Pennsylvania, his home state.
Dr. Block was the Founder and
Director of the Jefferson
Center
for Biomedical Research, which opened in the fall of 1997, and
was the result of a unique collaboration between Thomas
Jefferson
University
and the Hepatitis B Foundation. His goal was to bring scientists
interested in finding cures for hepatitis together in one place.
In the summer of 2004, Drexel
University
created a new research division, the Drexel Institute for
Biotechnology and Virus Research, located at the site of the
former Jefferson
Center. Dr. Block is also Founder and Director of the new Drexel
Institute.
Dr. Block entered college at
age 14 to study physics at the State University of New York. He
entered the life sciences as a graduate and postdoctoral student
at the State University of New York and
Princeton
Universities, respectively. At Oxford University, as a Sabbatical Fellow
working with Baruch S. Blumberg (Nobel Laureate) and Raymond
Dwek (Fellow, Royal Society), he discovered that a plant sugar,
called “NBDNJ” prevented the secretion of HBV from liver
cells without killing the cells. Further studies into the
mechanism of action of NBDNJ have led to important findings
regarding how the virus moves in the cell. NBDNJ has now
received the trade name “glycovir” and, in an improved form,
is being tested for its therapeutic potential in animals. It may
open the door to a new family of anti-hepatitis B agents and
provide a valuable tool in the fight against hepatitis B.
His other major discovery in
antiviral research is the development of a novel microorganism
based assay for antiviral drugs, called “MOBA”. In 1990, Dr.
Block received the WW Smith award for MOBA, which is patented
and currently used, or in development to search for many
antiviral agents. With others, in 1979, he also discovered the
phenomenon called “co-transformation” of mammalian cells,
which has served as the basis for introducing foreign DNA into
cultured cells and is universally used in research.
In 1998, he was named
“Scientist of the Year” by the American Liver Foundation (Delaware
Valley). He has received the “Special Public Service” award (with
his wife, Joan Block, RN) from the American Liver Foundation
(national board); “Visiting Distinguished Professor” at
Dongook University (South Korea); an Honorary Degree from The
Romanian Academy of Sciences for basic science advances in viral
hepatitis; and inducted into the Bulgarian National Academy of
Medicine and Sciences for his contributions to hepatitis B
research. The Daily Intelligencer newspaper named Dr. Block as
“One of the 100 most important people in
Bucks
County of the last century”.
Dr. Block serves on the Board
of Directors of the Hepatitis B Foundation, Institute for
Hepatitis and Virus Research, Delaware Valley Chapter of the
American Liver Foundation, and numerous other editorial and
professional boards. He serves on NIH study sections; has been
coordinator of several national and international meetings
focusing on hepatitis; elected Fellow, International Union
Against Cancer; elected Fellow, The Glycobiology Institute, University
of
Oxford; and has received many awards to perform research from the
National Institutes of Health and the U.S. Department of
Agriculture.
http://www.drexelmed.edu/med/microbiology_immunology/faculty/block.html
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